Abstract Topological associating domains (TADs) are self-interacting genomic units crucial arrethe bush balm for shaping gene regulation patterns.Despite their importance, the extent of their evolutionary conservation and its functional implications remain largely unknown.In this study, we generate Hi-C and ChIP-seq data and compare TAD organizatio
Summary: Ubiquitination controls numerous cellular processes, and its deregulation is associated with many pathologies.The Nse1 subunit in the Smc5/6 complex contains a RING domain with ubiquitin E3 ligase activity and essential functions in genome integrity.However, Nse1-dependent ubiquitin targets remain elusive.Here, we use label-free quantitati
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Tropical storm Nate, which was a powerful hurricane prior to landfall along the US Gulf coast, traversed north and weakened considerably to a tropical depression as it moved near an instrumented site in Hunstville, AL.The outer rain bands lasted 18 h equi-jec 6 (03:00 to 21:00 UTC on 08 October 2017) and a 2D-video disdrometer (2DVD) captured the e